Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

CREB3 Antikörper (C-Term)

CREB3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB50244 unconjugated
Produktnummer ABIN6242675
  • Target Alle CREB3 Antikörper anzeigen
    CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))
    Bindungsspezifität
    • 13
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 311-344, C-Term
    Reaktivität
    • 40
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 36
    • 3
    • 1
    Kaninchen
    Klonalität
    • 37
    • 3
    Polyklonal
    Konjugat
    • 23
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CREB3 Antikörper ist unkonjugiert
    Applikation
    • 31
    • 18
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This CREB3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 311-344 amino acids from the C-terminal region of human CREB3.
    Klon
    RB50244
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product CREB3 Primärantikörper
  • Applikationshinweise
    WB: 1:8000. WB: 1:8000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Target
    CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))
    Andere Bezeichnung
    CREB3 (CREB3 Produkte)
    Synonyme
    LUMAN antikoerper, LZIP antikoerper, AU044960 antikoerper, AW538053 antikoerper, C80076 antikoerper, LZIP-1 antikoerper, LZIP-2 antikoerper, Luman antikoerper, creb3 antikoerper, luman antikoerper, lzip antikoerper, cAMP responsive element binding protein 3 antikoerper, cAMP responsive element binding protein 3 S homeolog antikoerper, CREB3 antikoerper, Creb3 antikoerper, creb3.S antikoerper
    Hintergrund
    Endoplasmic reticulum (ER)-bound transcription factor that plays a role in the unfolded protein response (UPR). Involved in cell proliferation and migration, tumor suppression and inflammatory gene expression. Plays also a role in the human immunodeficiency virus type 1 (HIV-1) virus protein expression and in the herpes simplex virus-1 (HSV-1) latent infection and reactivation from latency. Isoform 2 plays a role in the unfolded protein response (UPR). Isoform 2 acts as a positive regulator of LKN-1/CCL15-induced chemotaxis signaling of leukocyte cell migration. Isoform 2 may play a role as a cellular tumor suppressor that is targeted by the hepatitis C virus (HSV) core protein. Isoform 2 represses the VP16-mediated transactivation of immediate early genes of the HSV-1 virus by sequestring host cell factor-1 HCFC1 in the ER membrane of sensory neurons, thereby preventing the initiation of the replicative cascade leading to latent infection. Isoform 3 functions as a negative transcriptional regulator in ligand-induced transcriptional activation of the glucocorticoid receptor NR3C1 by recruiting and activating histone deacetylases (HDAC1, HDAC2 and HDAC6). Isoform 3 decreases the acetylation level of histone H4. Isoform 3 does not promote the chemotactic activity of leukocyte cells.
    Molekulargewicht
    41379
    UniProt
    O43889
    Pathways
    Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Maintenance of Protein Location, Unfolded Protein Response
Sie sind hier:
Kundenservice