ZKSCAN3 Antikörper (AA 100-130)

Produktnummer ABIN6242712

Produktdetails anti-ZKSCAN3 Antikörper

Target: ZKSCAN3 (Zinc Finger Protein 306 (ZKSCAN3))

Bindungsspezifität: AA 100-130

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZKSCAN3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ZKSCAN3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 100-130 amino acids from human ZKSCAN3.

Klon: RB53917

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu ZKSCAN3

Target: ZKSCAN3 (Zinc Finger Protein 306 (ZKSCAN3))

Andere Bezeichnung: ZKSCAN3 (ZKSCAN3 Produkte)

Hintergrund: Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas.

Molekulargewicht: 60641

UniProt: Q9BRR0