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SYNE2 Antikörper (AA 1843-1877)

SYNE2 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB56750 unconjugated
Produktnummer ABIN6242751
  • Target Alle SYNE2 Antikörper anzeigen
    SYNE2 (Spectrin Repeat Containing, Nuclear Envelope 2 (SYNE2))
    Bindungsspezifität
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1843-1877
    Reaktivität
    • 14
    • 4
    • 1
    Human
    Wirt
    • 12
    • 4
    Kaninchen
    Klonalität
    • 12
    • 4
    Polyklonal
    Konjugat
    • 12
    • 2
    • 1
    • 1
    Dieser SYNE2 Antikörper ist unkonjugiert
    Applikation
    • 9
    • 8
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This SYNE2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1843-1877 amino acids from human SYNE2.
    Klon
    RB56750
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product SYNE2 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:25
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Target
    SYNE2 (Spectrin Repeat Containing, Nuclear Envelope 2 (SYNE2))
    Andere Bezeichnung
    SYNE2 (SYNE2 Produkte)
    Synonyme
    EDMD5 antikoerper, NUA antikoerper, NUANCE antikoerper, Nesp2 antikoerper, Nesprin-2 antikoerper, SYNE-2 antikoerper, TROPH antikoerper, SYNE2 antikoerper, nua antikoerper, edmd5 antikoerper, nuance antikoerper, syne-2 antikoerper, nesprin-2 antikoerper, 6820443O06Rik antikoerper, AW546258 antikoerper, D12Ertd777e antikoerper, Nesp2g antikoerper, mKIAA1011 antikoerper, RGD1305248 antikoerper, spectrin repeat containing nuclear envelope protein 2 antikoerper, spectrin repeat containing, nuclear envelope 2 antikoerper, SYNE2 antikoerper, syne2 antikoerper, Syne2 antikoerper
    Hintergrund
    Multi-isomeric modular protein which forms a linking network between organelles and the actin cytoskeleton to maintain the subcellular spatial organization. Component of SUN-protein- containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Involved in the maintenance of nuclear organization and structural integrity. Connects nuclei to the cytoskeleton by interacting with the nuclear envelope and with F-actin in the cytoplasm. Specifically, SYNE2 and SUN2 assemble in arrays of transmembrane actin-associated nuclear (TAN) lines which are bound to F-actin cables and couple the nucleus to retrograde actin flow during actin-dependent nuclear movement. Required for centrosome migration to the apical cell surface during early ciliogenesis.
    Molekulargewicht
    796442
    UniProt
    Q8WXH0
    Pathways
    Maintenance of Protein Location
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