MLL3 Antikörper (N-Term)

Produktnummer ABIN6242809

Produktdetails anti-MLL3 Antikörper

Target: MLL3 (KMT2C) (Histone-lysine N-methyltransferase 2C (KMT2C))

Bindungsspezifität: AA 1142-1175, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MLL3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MLL3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1142-1175 amino acids from the N-terminal region of human MLL3.

Klon: RB52487

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IHC-P: 1:25

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu MLL3

Target: MLL3 (KMT2C) (Histone-lysine N-methyltransferase 2C (KMT2C))

Andere Bezeichnung: MLL3 (KMT2C Produkte)

Synonyme: HALR antikoerper, MLL3 antikoerper, E330008K23Rik antikoerper, Mll3 antikoerper, mKIAA1506 antikoerper, lysine methyltransferase 2C antikoerper, lysine (K)-specific methyltransferase 2C antikoerper, KMT2C antikoerper, Kmt2c antikoerper

Hintergrund: Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Central component of the MLL2/3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation. KMT2C/MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder.

Molekulargewicht: 541370

UniProt: Q8NEZ4

Pathways: Warburg Effekt