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Sonic Hedgehog Antikörper (C-Term)

Name: Sonic Hedgehog Antikörper (C-Term)
SKU: ABIN6242829
Price: 445.5 EUR
Availability: InStock

SHH Reaktivität: Maus WB, FACS Wirt: Kaninchen Polyclonal RB51214 unconjugated

Western blot analysis of lysate from mouse liver tissue lysate, using Shh Antibody (C-term) (ABIN6242829 and ABIN6577864). (Sonic Hedgehog Antikörper (C-Term))

Flow cytometric analysis of Hela cells using (Mouse) Shh Antibody (C-term)(green, Cat(ABIN6242829 and ABIN6577864)) compared to an isotype control of rabbit IgG(blue). (Sonic Hedgehog Antikörper (C-Term))

FACS

2 Abbildungen

Produktnummer ABIN6242829

Datenblatt (PDF)

Target Alle Sonic Hedgehog (SHH) Antikörper anzeigen

Sonic Hedgehog (SHH)
Bindungsspezifität
15

12

9

5

4

4

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 397-431, C-Term
Reaktivität
66

49

37

17

10

6

6

5

2

2

2

1

1

1

1

1

1

1
Maus
Wirt
72

12

8

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
67

27
Polyklonal
Konjugat
51

8

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser Sonic Hedgehog Antikörper ist unkonjugiert
Applikation
68

28

23

14

13

11

9

6

6

6

5

4

3

1
Western Blotting (WB), Flow Cytometry (FACS)

Aufreinigung

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This Mouse Shh antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 397-431 amino acids from the C-terminal region of mouse Shh.

Klon

RB51214

Isotyp

Ig Fraction

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SHH Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Rind (Kuh), Pferd, Meerschweinchen, Ziege, Kaninchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated

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SHH Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal D6 unconjugated

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SHH Reaktivität: Human, Maus, Ratte WB, IF, IHC (p), FACS Wirt: Kaninchen Polyclonal RB52387 unconjugated

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SHH Reaktivität: Human, Ratte, Hund, Affe WB, IF Wirt: Maus Monoclonal 10H6 unconjugated

anti-Sonic Hedgehog (SHH) (AA 237-399) antibody
SHH Reaktivität: Ratte WB, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Sonic Hedgehog (SHH) (AA 203-218), (N-Term) antibody
SHH Reaktivität: Human, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB: 1:1000. FC: 1:25

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Haltbarkeit

6 months
Target

Sonic Hedgehog (SHH)

Andere Bezeichnung

Shh (SHH Produkte)

Synonyme

HHG1 antikoerper, HLP3 antikoerper, HPE3 antikoerper, MCOPCB5 antikoerper, SMMCI antikoerper, TPT antikoerper, TPTPS antikoerper, 9530036O11Rik antikoerper, Dsh antikoerper, Hhg1 antikoerper, Hx antikoerper, Hxl3 antikoerper, M100081 antikoerper, fc83d08 antikoerper, shh antikoerper, syu antikoerper, vhh-1 antikoerper, vhh1 antikoerper, wu:fc83d08 antikoerper, Xhh antikoerper, hedgehog antikoerper, xshh antikoerper, SHH antikoerper, twh antikoerper, twhh antikoerper, sonic hedgehog antikoerper, sonic hedgehog a antikoerper, sonic hedgehog L homeolog antikoerper, sonic hedgehog protein A antikoerper, sonic hedgehog b antikoerper, SHH antikoerper, Shh antikoerper, shha antikoerper, shh.L antikoerper, shh antikoerper, shhb antikoerper

Hintergrund

Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO. Also regulates another target, the gli oncogene. Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction (By similarity).

Molekulargewicht

47773

UniProt

Q62226

Pathways

Hedgehog Signalweg, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development