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KCNMA1 Antikörper (AA 118-152)
KCNMA1
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
RB53642
unconjugated
Produktnummer ABIN6242863
Produktdetails anti-KCNMA1 Antikörper
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Target
Alle KCNMA1 Antikörper anzeigen
KCNMA1
(Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1))
Bindungsspezifität
Alle Epitope für KCNMA1 Antikörper
AA 118-152
Reaktivität
Alle Reaktivitäten für KCNMA1 Antikörper
Human
Wirt
Alle Wirte für KCNMA1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für KCNMA1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für KCNMA1 Antikörper
Dieser KCNMA1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für KCNMA1 Antikörper
Western Blotting (WB)
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This KCNMA1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 118-152 amino acids from human KCNMA1.
Klon
RB53642
Isotyp
Ig Fraction
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Discover our top product KCNMA1 Primärantikörper
Alternativen
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anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (C-Term) antibody
KCNMA1
Reaktivität: Human, Ratte, Maus, Zebrafisch (Danio rerio), Rind (Kuh), Kaninchen, Hund, Pferd, Meerschweinchen, Schaf
WB, IHC
Wirt: Kaninchen
Polyclonal
unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (AA 1080-1129) antibody
KCNMA1
Reaktivität: Human, Ratte, Maus, Rind (Kuh), Kaninchen, Pferd, Meerschweinchen, Schaf, Huhn, Xenopus laevis, Affe, Schwein, Fledermaus
WB, IHC, IHC (p)
Wirt: Kaninchen
Polyclonal
unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (AA 1184-1200), (C-Term), (Intracellular) antibody
KCNMA1
Reaktivität: Human, Ratte, Maus
WB, IHC, IF, IP, ICC
Wirt: Kaninchen
Polyclonal
unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (AA 641-690) antibody
KCNMA1
Reaktivität: Human, Ratte, Maus, Zebrafisch (Danio rerio), Rind (Kuh), Kaninchen, Hund, Pferd, Meerschweinchen, Schaf, Affe, Schwein, Fledermaus
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Anwendungsinformationen
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Applikationshinweise
WB: 1:500
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Details zu KCNMA1
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Target
KCNMA1
(Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1))
Andere Bezeichnung
KCNMA1 (KCNMA1 Produkte )
Synonyme
BKTM antikoerper, KCa1.1 antikoerper, MaxiK antikoerper, SAKCA antikoerper, SLO antikoerper, SLO-ALPHA antikoerper, SLO1 antikoerper, bA205K10.1 antikoerper, mSLO1 antikoerper, DDBDRAFT_0190653 antikoerper, DDBDRAFT_0235401 antikoerper, DDB_0190653 antikoerper, DDB_0235401 antikoerper, KCNMA antikoerper, KCNMA1 antikoerper, 5730414M22Rik antikoerper, BKCa antikoerper, Slo antikoerper, Slo1 antikoerper, mSlo antikoerper, mSlo1 antikoerper, KCNMA1b antikoerper, KCNMA1c antikoerper, Kcnma antikoerper, bktm antikoerper, kcnma1-A antikoerper, sakca antikoerper, cSlo antikoerper, slo1 antikoerper, kcnma1 antikoerper, si:ch211-39f22.2 antikoerper, BcDNA:GH10751 antikoerper, CG10693 antikoerper, Dmel\CG10693 antikoerper, Dslo antikoerper, dSlo antikoerper, dSlo1 antikoerper, dslo antikoerper, fSlo antikoerper, potassium calcium-activated channel subfamily M alpha 1 antikoerper, calcium-activated BK potassium channel, alpha subunit antikoerper, potassium large conductance calcium-activated channel, subfamily M, alpha member 1 antikoerper, potassium calcium-activated channel subfamily M alpha 1 L homeolog antikoerper, potassium large conductance calcium-activated channel, subfamily M, alpha member 1a antikoerper, calcium-activated potassium channel subunit alpha-1 antikoerper, slowpoke antikoerper, KCNMA1 antikoerper, kcnma1 antikoerper, Kcnma1 antikoerper, kcnma1.L antikoerper, kcnma1a antikoerper, LOC100454095 antikoerper, slo antikoerper
Hintergrund
Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in the cochlea, regulation of transmitter release, and innate immunity. In smooth muscles, its activation by high level of Ca(2+), caused by ryanodine receptors in the sarcoplasmic reticulum, regulates the membrane potential. In cochlea cells, its number and kinetic properties partly determine the characteristic frequency of each hair cell and thereby helps to establish a tonotopic map. Kinetics of KCNMA1 channels are determined by alternative splicing, phosphorylation status and its combination with modulating beta subunits. Highly sensitive to both iberiotoxin (IbTx) and charybdotoxin (CTX).
Molekulargewicht
137560
UniProt
Q12791
Pathways
Regulation of Hormone Metabolic Process , Sensory Perception of Sound
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