NCR3 Antikörper (AA 31-65)

Produktnummer ABIN6242894

Produktdetails anti-NCR3 Antikörper

Target: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Bindungsspezifität: AA 31-65

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCR3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: H

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NCR3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 31-65 amino acids from the human region of human NCR3.

Klon: RB57884

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu NCR3

Target: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Andere Bezeichnung: NCR3 (NCR3 Produkte)

Synonyme: MGC133750 antikoerper, 1C7 antikoerper, CD337 antikoerper, LY117 antikoerper, MALS antikoerper, NKp30 antikoerper, Nkp30 antikoerper, natural cytotoxicity triggering receptor 3 antikoerper, NCR3 antikoerper, Ncr3 antikoerper

Hintergrund: Cytotoxicity-activating receptor that contributes to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.

Molekulargewicht: 21593

UniProt: O14931

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process