LECT1 Antikörper (N-Term)

Produktnummer ABIN6242902

Produktdetails anti-LECT1 Antikörper

Target: LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))

Bindungsspezifität: AA 1-30, N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LECT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: B, Rb

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LECT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human LECT1.

Klon: RB15072

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu LECT1

Target: LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))

Andere Bezeichnung: LECT1 (LECT1 Produkte)

Synonyme: chm1 antikoerper, chm-i antikoerper, bricd3 antikoerper, MGC53801 antikoerper, MGC82444 antikoerper, chondromodulin-I antikoerper, Lect1 antikoerper, BRICD3 antikoerper, CHM-I antikoerper, CHM1 antikoerper, MYETS1 antikoerper, Bricd3 antikoerper, ChM-I antikoerper, Chm-1 antikoerper, chondromodulin L homeolog antikoerper, leukocyte cell derived chemotaxin 1 antikoerper, chondromodulin antikoerper, cnmd.L antikoerper, lect1 antikoerper, CNMD antikoerper, cnmd antikoerper, Cnmd antikoerper

Hintergrund: LECT1 is a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This protein expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development.

Molekulargewicht: 37102

NCBI Accession: NP_001011705, NP_008946

UniProt: O75829