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Reticulon 4 Antikörper (AA 28-58)

Name: Reticulon 4 Antikörper (AA 28-58)
SKU: ABIN6242947
Price: 445.5 EUR
Availability: InStock

RTN4 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB54371 unconjugated

Anti-RTN4 Antibody (N-Term) at 1:2000 dilution + human brain lysate Lysates/proteins at 20 μg per lane. (Reticulon 4 Antikörper (AA 28-58))

1 image

Produktnummer ABIN6242947

Datenblatt (PDF)

Target Alle Reticulon 4 (RTN4) Antikörper anzeigen

Reticulon 4 (RTN4)
Bindungsspezifität
16

15

4

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 28-58
Reaktivität
74

55

44

6

4

4

4

4

4

3

2

2

1

1
Human
Wirt
71

3

3

2

2
Kaninchen
Passende Sekundärantikörper
Klonalität
68

13
Polyklonal
Konjugat
35

4

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1
Dieser Reticulon 4 Antikörper ist unkonjugiert
Applikation
64

28

27

21

18

17

17

9

6

3

2

1

1
Western Blotting (WB)

Homologie

M, Rat

Aufreinigung

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This RTN4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 28-58 amino acids from human RTN4.

Klon

RB54371

Isotyp

Ig Fraction

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anti-Reticulon 4 (RTN4) (N-Term) antibody
RTN4 Reaktivität: Human, Maus, Ratte WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB: 1:2000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Haltbarkeit

6 months
Target

Reticulon 4 (RTN4)

Andere Bezeichnung

RTN4 (RTN4 Produkte)

Synonyme

ASY antikoerper, NI220/250 antikoerper, NOGO antikoerper, NOGO-A antikoerper, NOGOC antikoerper, NSP antikoerper, NSP-CL antikoerper, Nbla00271 antikoerper, Nbla10545 antikoerper, Nogo-B antikoerper, Nogo-C antikoerper, RTN-X antikoerper, RTN4-A antikoerper, RTN4-B1 antikoerper, RTN4-B2 antikoerper, RTN4-C antikoerper, RTN4-Cw antikoerper, DKFZp459C0314 antikoerper, 1110020G17Rik antikoerper, AA407876 antikoerper, AA409940 antikoerper, AA960376 antikoerper, C130026I10Rik antikoerper, NgA antikoerper, Nogo-A antikoerper, mKIAA0886 antikoerper, mKIAA4153 antikoerper, NI-250 antikoerper, Nogo antikoerper, Vp20 antikoerper, r antikoerper, rat N antikoerper, rat NogoA antikoerper, reticulon-4 antikoerper, nogo antikoerper, rtn4 antikoerper, wu:fb17a02 antikoerper, wu:fb22f12 antikoerper, wu:fd61a07 antikoerper, zgc:92163 antikoerper, reticulon 4 antikoerper, reticulon 4a antikoerper, RTN4 antikoerper, rtn4 antikoerper, Rtn4 antikoerper, rtn4a antikoerper

Hintergrund

Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching. Regulates neurite fasciculation, branching and extension in the developing nervous system. Involved in down-regulation of growth, stabilization of wiring and restriction of plasticity in the adult CNS. Regulates the radial migration of cortical neurons via an RTN4R-LINGO1 containing receptor complex (By similarity). Isoform 2 reduces the anti-apoptotic activity of Bcl-xl and Bcl-2. This is likely consecutive to their change in subcellular location, from the mitochondria to the endoplasmic reticulum, after binding and sequestration. Isoform 2 and isoform 3 inhibit BACE1 activity and amyloid precursor protein processing.

Molekulargewicht

129931

UniProt

Q9NQC3

Pathways

Neurotrophin Signalübertragung, Regulation of Cell Size, SARS-CoV-2 Protein Interaktom