NMNAT1 Antikörper (AA 200-232)

Produktnummer ABIN6242969

Produktdetails anti-NMNAT1 Antikörper

Target: NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))

Bindungsspezifität: AA 200-232

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NMNAT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: B, M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NMNAT1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 200-232 amino acids from human NMNAT1.

Klon: RB55363

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000. WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu NMNAT1

Target: NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))

Andere Bezeichnung: NMNAT1 (NMNAT1 Produkte)

Synonyme: id:ibd5068 antikoerper, im:7144541 antikoerper, zgc:110243 antikoerper, LCA9 antikoerper, NMNAT antikoerper, PNAT1 antikoerper, 2610529L11Rik antikoerper, 5730441G13Rik antikoerper, D4Cole1e antikoerper, nmnat antikoerper, nicotinamide mononucleotide adenylyltransferase 1 antikoerper, nicotinamide nucleotide adenylyltransferase 1 antikoerper, CpipJ_CPIJ015320 antikoerper, PTRG_06486 antikoerper, nmnat1 antikoerper, NMNAT1 antikoerper, Nmnat1 antikoerper

Hintergrund: Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form, nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, prefers NAD(+) and NAAD as substrates and degrades NADH, nicotinic acid adenine dinucleotide phosphate (NHD) and nicotinamide guanine dinucleotide (NGD) less effectively. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NAADP(+). Protects against axonal degeneration following mechanical or toxic insults.

Molekulargewicht: 31932

UniProt: Q9HAN9