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PPID Antikörper (AA 336-370)

PPID Reaktivität: Human WB, IHC (p), FACS, IF Wirt: Kaninchen Polyclonal RB55961 unconjugated
Produktnummer ABIN6243007
  • Target Alle PPID Antikörper anzeigen
    PPID (Peptidylprolyl Isomerase D (PPID))
    Bindungsspezifität
    • 12
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 336-370
    Reaktivität
    • 42
    • 19
    • 15
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 37
    • 6
    • 1
    Kaninchen
    Klonalität
    • 40
    • 4
    Polyklonal
    Konjugat
    • 39
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PPID Antikörper ist unkonjugiert
    Applikation
    • 36
    • 16
    • 12
    • 11
    • 10
    • 10
    • 8
    • 7
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (IF)
    Homologie
    M, Rat
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This Cyclophilin D antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 336-370 amino acids from the human region of human Cyclophilin D.
    Klon
    RB55961
    Isotyp
    Ig Fraction
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  • Applikationshinweise
    IF: 1:25. WB: 1:2000. IHC-P: 1:25. FC: 1:25. FC: 1:25
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Target
    PPID (Peptidylprolyl Isomerase D (PPID))
    Andere Bezeichnung
    Cyclophilin D (PPID Produkte)
    Synonyme
    PPID antikoerper, CYP-40 antikoerper, CYPD antikoerper, Cyp-40 antikoerper, CypD antikoerper, wu:fb18b07 antikoerper, zgc:86711 antikoerper, 4930564J03Rik antikoerper, Ppidl antikoerper, Ppif antikoerper, cyp-40 antikoerper, cypd antikoerper, peptidylprolyl isomerase D antikoerper, peptidylprolyl isomerase D (cyclophilin D) antikoerper, peptidylprolyl isomerase D (cyclophilin D) S homeolog antikoerper, PPID antikoerper, Ppid antikoerper, ppid antikoerper, ppid.S antikoerper
    Hintergrund
    PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Proposed to act as a co-chaperone in HSP90 complexes such as in unligated steroid receptors heterocomplexes. Different co-chaperones seem to compete for association with HSP90 thus establishing distinct HSP90-co-chaperone-receptor complexes with the potential to exert tissue-specific receptor activity control. May have a preference for estrogen receptor complexes and is not found in glucocorticoid receptor complexes. May be involved in cytoplasmic dynein-dependent movement of the receptor from the cytoplasm to the nucleus. May regulate MYB by inhibiting its DNA- binding activity. Involved in regulation of AHR signaling by promoting the formation of the AHR:ARNT dimer, the function is independent of HSP90 but requires the chaperone activity. Involved in regulation of UV radiation-induced apoptosis. Promotes cell viability in anaplastic lymphoma kinase-positive anaplastic large- cell lymphoma (ALK+ ALCL) cell lines. May be involved in hepatitis C virus (HCV) replication and release.
    Molekulargewicht
    40764
    UniProt
    Q08752
    Pathways
    Nuclear Hormone Receptor Binding
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