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RAF1 Antikörper (AA 599-628)

Name: RAF1 Antikörper (AA 599-628)
SKU: ABIN6243077
Price: 445.5 EUR
Availability: InStock

RAF1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB13293 unconjugated

Western blot analysis of RAF1 (arrow) using rabbit polyclonal RAF1 Antibody (ABIN6243077 and ABIN6579013). (RAF1 Antikörper (AA 599-628))

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with RAF1-p, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (RAF1 Antikörper (AA 599-628))

IHC (p)

Anti-RAF1 Antibody at 1:1000 dilution + MCF-7 whole cell lysate Lysates/proteins at 20 μg per lane. (RAF1 Antikörper (AA 599-628))

3 Abbildungen

Produktnummer ABIN6243077

Datenblatt (PDF)

Target Alle RAF1 Antikörper anzeigen

RAF1 (V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1))
Bindungsspezifität
49

46

35

34

33

31

24

24

23

22

20

18

15

14

13

8

8

8

7

6

6

6

6

5

4

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1
AA 599-628
Reaktivität
463

241

168

14

13

12

12

9

5

4

4

2

2

2

2

1

1
Human
Wirt
495

14

2

2
Kaninchen
Passende Sekundärantikörper
Klonalität
473

40
Polyklonal
Konjugat
206

37

28

27

17

16

12

12

12

12

12

12

10

10

10

10

10

10

10

10

10

10

10
Dieser RAF1 Antikörper ist unkonjugiert
Applikation
301

223

105

104

96

73

46

31

30

24

16

11

8

3

2

2

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie

B, C, M, Rat

Aufreinigung

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This RAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 599-628 amino acids from human RAF1.

Klon

RB13293

Isotyp

Ig Fraction

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RAF1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) (pSer259) antibody
RAF1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) (AA 1-648) antibody
RAF1 Reaktivität: Human WB, ELISA, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated

anti-V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) (AA 1-30), (N-Term) antibody
RAF1 Reaktivität: Human WB, IF, IHC (p), FACS Wirt: Kaninchen Polyclonal RB3329 unconjugated

anti-V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) antibody
RAF1 Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) (pSer338) antibody
RAF1 Reaktivität: Human, Maus, Ratte WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Haltbarkeit

6 months
Target

RAF1 (V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1))

Andere Bezeichnung

RAF1 (RAF1 Produkte)

Synonyme

CRAF antikoerper, NS5 antikoerper, Raf-1 antikoerper, c-Raf antikoerper, c-raf antikoerper, craf antikoerper, raf1 antikoerper, RAF1 antikoerper, 6430402F14Rik antikoerper, AA990557 antikoerper, BB129353 antikoerper, Craf1 antikoerper, D830050J10Rik antikoerper, v-Raf antikoerper, raf antikoerper, cRaf antikoerper, Raf-1 proto-oncogene, serine/threonine kinase antikoerper, Raf-1 proto-oncogene, serine/threonine kinase a antikoerper, v-raf-leukemia viral oncogene 1 antikoerper, Raf-1 proto-oncogene, serine/threonine kinase S homeolog antikoerper, RAF1 antikoerper, Raf1 antikoerper, raf1a antikoerper, raf1 antikoerper, raf1.S antikoerper

Hintergrund

RAF1 is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, RAF1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylate to activate the serine/threonine specific protein kinases ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration.

Molekulargewicht

73052

NCBI Accession

NP_002871

UniProt

P04049

Pathways

MAPK Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, cAMP Metabolic Process, Stem Cell Maintenance, Hepatitis C, Autophagie, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling, BCR Signaling