CYR61 Antikörper (AA 143-174)

Produktnummer ABIN6243134

Produktdetails anti-CYR61 Antikörper

Target: CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))

Bindungsspezifität: AA 143-174

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYR61 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CYR61 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 143-174 amino acids from the Central region of human CYR61.

Klon: RB53929

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu CYR61

Target: CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))

Andere Bezeichnung: CYR61 (CYR61 Produkte)

Synonyme: CCN1 antikoerper, GIG1 antikoerper, IGFBP10 antikoerper, ccn1 antikoerper, gig1 antikoerper, Xcyr61 antikoerper, igfbp10 antikoerper, MGC69281 antikoerper, MGC69539 antikoerper, cyr61-l2 antikoerper, zgc:158158 antikoerper, CYR61 antikoerper, AI325051 antikoerper, Igfbp10 antikoerper, cysteine rich angiogenic inducer 61 antikoerper, cysteine-rich, angiogenic inducer, 61 antikoerper, cysteine-rich, angiogenic inducer, 61 like 2 antikoerper, cysteine rich protein 61 antikoerper, cysteine rich angiogenic inducer 61 S homeolog antikoerper, CYR61 antikoerper, Cyr61 antikoerper, cyr61 antikoerper, cyr61l2 antikoerper, cyr61.S antikoerper

Hintergrund: Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up- regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3.

Molekulargewicht: 42027

UniProt: O00622

Pathways: Positive Regulation of Endopeptidase Activity, Growth Factor Binding