DIABLO Antikörper (C-Term)
(1 reference)-
- Target Alle DIABLO Antikörper anzeigen
- DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))
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Bindungsspezifität
- AA 211-239, C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser DIABLO Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
- Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This SMAC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-239 amino acids from the C-terminal region of human SMAC.
- Klon
- RB20755
- Isotyp
- Ig Fraction
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anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 1-232) antibody
DIABLO Reaktivität: Human WB, IHC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 131-239) antibodyDIABLO Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) antibodyDIABLO Reaktivität: Human, Affe WB, IHC (p) Wirt: Maus Monoclonal 79-1-83 unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 56-239) antibodyDIABLO Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 168-236) antibodyDIABLO Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 1-239) antibodyDIABLO Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (C-Term) antibodyDIABLO Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 225-239) antibodyDIABLO Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 1-239) antibodyDIABLO Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 119-218) antibodyDIABLO Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 4F9 unconjugated
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- Applikationshinweise
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
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-
: "A novel small-molecule inhibitor of mcl-1 blocks pancreatic cancer growth in vitro and in vivo." in: Molecular cancer therapeutics, Vol. 13, Issue 3, pp. 565-75, (2014) (PubMed).
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: "A novel small-molecule inhibitor of mcl-1 blocks pancreatic cancer growth in vitro and in vivo." in: Molecular cancer therapeutics, Vol. 13, Issue 3, pp. 565-75, (2014) (PubMed).
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- Target
- DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))
- Andere Bezeichnung
- SMAC (DIABLO Produkte)
- Hintergrund
- SMAC is an inhibitor of apoptosis protein (IAP)-binding protein. This mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs.
- Molekulargewicht
- 27131
- NCBI Accession
- NP_001265231, NP_001265232, NP_001265233, NP_001265271, NP_063940, NP_620308
- UniProt
- Q9NR28
- Pathways
- Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity
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