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GPR56 Antikörper

GPR56 Reaktivität: Human WB Wirt: Maus Monoclonal 1443CT377-65-29 unconjugated
Produktnummer ABIN6243208
  • Target Alle GPR56 Antikörper anzeigen
    GPR56 (G Protein-Coupled Receptor 56 (GPR56))
    Reaktivität
    • 44
    • 22
    • 5
    • 4
    • 2
    Human
    Wirt
    • 36
    • 8
    Maus
    Klonalität
    • 39
    • 5
    Monoklonal
    Konjugat
    • 24
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GPR56 Antikörper ist unkonjugiert
    Applikation
    • 33
    • 21
    • 15
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Immunogen
    This antibody is generated from a mouse immunized with a recombinant protein.
    Klon
    1443CT377-65-29
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product GPR56 Primärantikörper
  • Applikationshinweise
    WB: 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Target
    GPR56 (G Protein-Coupled Receptor 56 (GPR56))
    Andere Bezeichnung
    GPR56 (GPR56 Produkte)
    Hintergrund
    Involved in cell adhesion and probably in cell-cell interactions. Regulates the migration of neural precursor cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basemant membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Isoforms show differences in receptor signaling, specifically in serum response element (SRE) transcriptional activation upon overexpression. Overexpression inhibits melanoma tumor growth and metastasis and, during melanoma progression, regulates VEGFA production and angiogenesis through PRKCA, unprocessed GPR56 is inhibiting and GPR56 NT is activating angiogenesis.
    Molekulargewicht
    77738
    UniProt
    Q9Y653
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