HSD17B10 Antikörper (AA 140-172)

Produktnummer ABIN6243230

Produktdetails anti-HSD17B10 Antikörper

Target: HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))

Bindungsspezifität: AA 140-172

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSD17B10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Homologie: B

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HSD17B10 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 140-172 amino acids from the Central region of human HSD17B10.

Klon: RB56913

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:25. WB: 1:2000. IHC-P: 1:25. FC: 1:25

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu HSD17B10

Target: HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))

Andere Bezeichnung: HSD17B10 (HSD17B10 Produkte)

Synonyme: hadh2 antikoerper, im:6899159 antikoerper, wu:fj61f03 antikoerper, zgc:101605 antikoerper, abad antikoerper, camr antikoerper, erab antikoerper, hcd2 antikoerper, hsd10 antikoerper, mhbd antikoerper, mrpp2 antikoerper, mrx17 antikoerper, mrx31 antikoerper, mrxs10 antikoerper, schad antikoerper, sdr5c1 antikoerper, HADH2 antikoerper, HSD17B10 antikoerper, 17b-HSD10 antikoerper, ABAD antikoerper, CAMR antikoerper, DUPXp11.22 antikoerper, ERAB antikoerper, HCD2 antikoerper, MHBD antikoerper, MRPP2 antikoerper, MRX17 antikoerper, MRX31 antikoerper, MRXS10 antikoerper, SCHAD antikoerper, SDR5C1 antikoerper, 17bHSD10 antikoerper, Ads9 antikoerper, Hadh2 antikoerper, hydroxysteroid (17-beta) dehydrogenase 10 antikoerper, hydroxysteroid 17-beta dehydrogenase 10 antikoerper, hydroxysteroid (17-beta) dehydrogenase 10 L homeolog antikoerper, HSD17B10 antikoerper, hsd17b10 antikoerper, hsd17b10.L antikoerper, Hsd17b10 antikoerper

Hintergrund: Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).

Molekulargewicht: 26923

UniProt: Q99714