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HSD17B10 Antikörper (AA 14-48)

HSD17B10 Reaktivität: Human WB, IF, FACS Wirt: Kaninchen Polyclonal RB56756 unconjugated
Produktnummer ABIN6243231
  • Target Alle HSD17B10 Antikörper anzeigen
    HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))
    Bindungsspezifität
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 14-48
    Reaktivität
    • 54
    • 23
    • 17
    • 3
    • 2
    • 2
    • 2
    Human
    Wirt
    • 45
    • 9
    • 1
    Kaninchen
    Klonalität
    • 48
    • 7
    Polyklonal
    Konjugat
    • 34
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser HSD17B10 Antikörper ist unkonjugiert
    Applikation
    • 31
    • 18
    • 15
    • 14
    • 11
    • 10
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This HSD17B10 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 14-48 amino acids from human HSD17B10.
    Klon
    RB56756
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product HSD17B10 Primärantikörper
  • Applikationshinweise
    IF: 1:25. WB: 1:8000. FC: 1:25
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Target
    HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))
    Andere Bezeichnung
    HSD17B10 (HSD17B10 Produkte)
    Hintergrund
    Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).
    Molekulargewicht
    26923
    UniProt
    Q99714
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