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RUNX2 Antikörper (N-Term)

RUNX2 Reaktivität: Human IHC (p) Wirt: Kaninchen Polyclonal RB10543 unconjugated
Produktnummer ABIN6243280
  • Target Alle RUNX2 Antikörper anzeigen
    RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
    Bindungsspezifität
    • 16
    • 16
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    Reaktivität
    • 115
    • 46
    • 30
    • 10
    • 9
    • 8
    • 8
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 105
    • 12
    Kaninchen
    Klonalität
    • 98
    • 19
    Polyklonal
    Konjugat
    • 59
    • 8
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RUNX2 Antikörper ist unkonjugiert
    Applikation
    • 92
    • 46
    • 31
    • 25
    • 10
    • 9
    • 9
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This RUNX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of human RUNX2.
    Klon
    RB10543
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product RUNX2 Primärantikörper
  • Applikationshinweise
    IHC-P: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Ushijima, Okazaki, Tsushima, Iwamoto: "CCAAT/enhancer-binding protein β regulates the repression of type II collagen expression during the differentiation from proliferative to hypertrophic chondrocytes." in: The Journal of biological chemistry, Vol. 289, Issue 5, pp. 2852-63, (2014) (PubMed).

  • Target
    RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
    Andere Bezeichnung
    RUNX2 (RUNX2 Produkte)
    Hintergrund
    Runx2 is a member of the RUNX family of transcription factors. It is a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. It can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in the Runx2 gene have been associated with the bone development disorder cleidocranial dysplasia (CCD).
    Molekulargewicht
    56648
    NCBI Accession
    NP_001015051, NP_001019801
    UniProt
    Q13950
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