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ULK3 Antikörper (C-Term)

ULK3 Reaktivität: Human, Maus, Ratte WB Wirt: Maus Monoclonal 1404CT148-89-25 unconjugated
Produktnummer ABIN6243328
  • Target Alle ULK3 Antikörper anzeigen
    ULK3 (Unc-51-Like Kinase 3 (ULK3))
    Bindungsspezifität
    • 14
    • 10
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 435-468, C-Term
    Reaktivität
    • 54
    • 45
    • 15
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 62
    • 6
    • 2
    Maus
    Klonalität
    • 65
    • 5
    Monoklonal
    Konjugat
    • 31
    • 6
    • 6
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ULK3 Antikörper ist unkonjugiert
    Applikation
    • 61
    • 40
    • 11
    • 10
    • 9
    • 6
    • 3
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    Immunogen
    This ULK3 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 435-468 amino acids from the C-terminal region of human ULK3.
    Klon
    1404CT148-89-25
    Isotyp
    IgG1 kappa
    Top Product
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  • Applikationshinweise
    IHC: 1:50. WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Target
    ULK3 (Unc-51-Like Kinase 3 (ULK3))
    Andere Bezeichnung
    ULK3 (ULK3 Produkte)
    Synonyme
    zgc:162196 antikoerper, 1200015E14Rik antikoerper, unc-51 like kinase 3 antikoerper, unc-51 like kinase 3 L homeolog antikoerper, unc-51-like kinase 3 antikoerper, ULK3 antikoerper, ulk3 antikoerper, Ulk3 antikoerper, ulk3.L antikoerper
    Hintergrund
    Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3). Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. Also acts as a regulator of autophagy: following cellular senescence, able to induce autophagy.
    Molekulargewicht
    53444
    UniProt
    Q6PHR2
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