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UBE2D2 Antikörper (N-Term)

UBE2D2 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal RB49628 unconjugated
Produktnummer ABIN6243331
  • Target Alle UBE2D2 Antikörper anzeigen
    UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))
    Bindungsspezifität
    • 15
    • 9
    • 8
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 44-76, N-Term
    Reaktivität
    • 62
    • 32
    • 16
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 55
    • 7
    Kaninchen
    Klonalität
    • 56
    • 6
    Polyklonal
    Konjugat
    • 33
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser UBE2D2 Antikörper ist unkonjugiert
    Applikation
    • 50
    • 22
    • 13
    • 13
    • 9
    • 9
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This UBE2D2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 44-76 amino acids from the N-terminal region of human UBE2D2.
    Klon
    RB49628
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product UBE2D2 Primärantikörper
  • Applikationshinweise
    WB: 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Target
    UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))
    Andere Bezeichnung
    UBE2D2 (UBE2D2 Produkte)
    Hintergrund
    Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP- induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection. Essential for viral activation of IRF3.
    Molekulargewicht
    16735
    UniProt
    P62837
    Pathways
    Activation of Innate immune Response, Toll-Like Receptors Cascades
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