TNRC6A Antikörper (AA 855-885)

Produktnummer ABIN6243375

Produktdetails anti-TNRC6A Antikörper

Target: TNRC6A (Trinucleotide Repeat Containing 6A (TNRC6A))

Bindungsspezifität: AA 855-885

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TNRC6A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 855-885 amino acids from the Central region of human TNRC6A.

Klon: RB54170

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu TNRC6A

Target: TNRC6A (Trinucleotide Repeat Containing 6A (TNRC6A))

Andere Bezeichnung: TNRC6A

Synonyme: 2010321I05Rik antikoerper, 3110054G10Rik antikoerper, AW557223 antikoerper, CAGH26 antikoerper, D130023A07Rik antikoerper, GW182 antikoerper, Tnrc6 antikoerper, GW1 antikoerper, TNRC6 antikoerper, trinucleotide repeat containing 6a antikoerper, trinucleotide repeat containing 6A antikoerper, Tnrc6a antikoerper, TNRC6A antikoerper

Hintergrund: Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent repression of translation and for siRNA- dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. As scaffoldng protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes.

Molekulargewicht: 210297

UniProt: Q8NDV7