UHMK1 Antikörper (C-Term)

Produktnummer ABIN6243411

Produktdetails anti-UHMK1 Antikörper

Target: UHMK1 (U2AF Homology Motif (UHM) Kinase 1 (UHMK1))

Bindungsspezifität: AA 265-295, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UHMK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: Rat

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This KIST (KIS) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-295 amino acids from the C-terminal region of human KIST (KIS).

Klon: RB5431

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu UHMK1

Target: UHMK1 (U2AF Homology Motif (UHM) Kinase 1 (UHMK1))

Andere Bezeichnung: KIST (KIS) (UHMK1 Produkte)

Synonyme: UHMK1 antikoerper, zgc:153241 antikoerper, KIS antikoerper, KIST antikoerper, P-CIP2 antikoerper, 4732477C12Rik antikoerper, 4930500M09Rik antikoerper, AA673513 antikoerper, AI449218 antikoerper, AU021979 antikoerper, Kist antikoerper, U2AF homology motif kinase 1 antikoerper, U2AF homology motif (UHM) kinase 1 antikoerper, UHMK1 antikoerper, uhmk1 antikoerper, Uhmk1 antikoerper

Hintergrund: KIST, a member of the Ser/Thr protein kinase family, is a pyruvate kinase that catalyzes formation of phosphoenolpyruvate from pyruvate and ATP. A role for the primarily nuclear KIST protein in mediation of cellular metabolism has been postulated based on the interaction identified with thyroid hormone. KIST is widely expressed, with highest abundance in skeletal muscle, kidney, placenta and peripheral blood leukocytes. Upon serum stimulation, KIST phosphorylates CDKN1B/p27Kip1, thereby regulating the subcellular location of CDKN1B and cell cycle progression in the G1 phase. KIST, which contains one RNA recognition motif domain, has been proposed to partipate in trafficking and processing of RNA. KIST binds to Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells.

Molekulargewicht: 46546

NCBI Accession: NP_001171692, NP_653225, NP_787062

UniProt: Q8TAS1