CBX7 Antikörper (C-Term)
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- Target Alle CBX7 Antikörper anzeigen
- CBX7 (Chromobox Homolog 7 (CBX7))
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Bindungsspezifität
- AA 144-178, C-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CBX7 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This Mouse Cbx7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 144-178 amino acids from the C-terminal region of human Mouse Cbx7.
- Klon
- RB50982
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product CBX7 Primärantikörper
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- Applikationshinweise
- WB: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
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- Target
- CBX7 (Chromobox Homolog 7 (CBX7))
- Andere Bezeichnung
- Cbx7 (CBX7 Produkte)
- Synonyme
- 1600014J01Rik antikoerper, AI851678 antikoerper, D15Ertd417e antikoerper, zgc:110152 antikoerper, chromobox 7 antikoerper, chromobox homolog 7a antikoerper, CBX7 antikoerper, Cbx7 antikoerper, cbx7a antikoerper
- Hintergrund
- Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to histone H3 trimethylated 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3). May possibly also bind trimethylated lysine residues in other proteins (in vitro). Binds non-coding, single-stranded RNA. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.
- Molekulargewicht
- 18109
- UniProt
- Q8VDS3
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