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CBX7 Antikörper (C-Term)

CBX7 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal RB50982 unconjugated
Produktnummer ABIN6243434
  • Target Alle CBX7 Antikörper anzeigen
    CBX7 (Chromobox Homolog 7 (CBX7))
    Bindungsspezifität
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 144-178, C-Term
    Reaktivität
    • 33
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 28
    • 4
    • 1
    Kaninchen
    Klonalität
    • 23
    • 10
    Polyklonal
    Konjugat
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser CBX7 Antikörper ist unkonjugiert
    Applikation
    • 17
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This Mouse Cbx7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 144-178 amino acids from the C-terminal region of human Mouse Cbx7.
    Klon
    RB50982
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product CBX7 Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Target
    CBX7 (Chromobox Homolog 7 (CBX7))
    Andere Bezeichnung
    Cbx7 (CBX7 Produkte)
    Synonyme
    1600014J01Rik antikoerper, AI851678 antikoerper, D15Ertd417e antikoerper, zgc:110152 antikoerper, chromobox 7 antikoerper, chromobox homolog 7a antikoerper, CBX7 antikoerper, Cbx7 antikoerper, cbx7a antikoerper
    Hintergrund
    Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to histone H3 trimethylated 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3). May possibly also bind trimethylated lysine residues in other proteins (in vitro). Binds non-coding, single-stranded RNA. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.
    Molekulargewicht
    18109
    UniProt
    Q8VDS3
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