PCGF6 Antikörper (C-Term)

Produktnummer ABIN6243439

Produktdetails anti-PCGF6 Antikörper

Target: PCGF6 (Polycomb Group Ring Finger 6 (PCGF6))

Bindungsspezifität: AA 261-295, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCGF6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PCGF6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 261-295 amino acids from the C-terminal region of human PCGF6.

Klon: RB51296

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:25. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu PCGF6

Target: PCGF6 (Polycomb Group Ring Finger 6 (PCGF6))

Andere Bezeichnung: PCGF6 (PCGF6 Produkte)

Synonyme: im:7144322 antikoerper, si:ch211-67n3.7 antikoerper, MBLR antikoerper, RNF134 antikoerper, 4933407A11Rik antikoerper, AI604840 antikoerper, Rnf134 antikoerper, polycomb group ring finger 6 antikoerper, PCGF6 antikoerper, pcgf6 antikoerper, Pcgf6 antikoerper

Hintergrund: Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Molekulargewicht: 39047

UniProt: Q9BYE7