ALK Antikörper (AA 636-666)

Produktnummer ABIN6243477

Produktdetails anti-ALK Antikörper

Target: ALK (Anaplastic Lymphoma Receptor tyrosine Kinase (ALK))

Bindungsspezifität: AA 636-666

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALK Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This ALK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 636-666 amino acids from the Central region of human ALK.

Klon: RB15425

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu ALK

Target: ALK (Anaplastic Lymphoma Receptor tyrosine Kinase (ALK))

Andere Bezeichnung: ALK (ALK Produkte)

Synonyme: Tcrz antikoerper, CD246 antikoerper, NBLST3 antikoerper, ALK antikoerper, anaplastic lymphoma kinase antikoerper, anaplastic lymphoma receptor tyrosine kinase antikoerper, ALK receptor tyrosine kinase antikoerper, Alk antikoerper, ALK antikoerper

Hintergrund: ALK, a member of the insulin receptor subfamily of Tyr protein kinases, is an orphan receptor. It appears to play an important role in the normal development and function of the nervous system. This Type I membrane protein is expressed in brain and CNS and in the small intestine and testis, but not in normal lymphoid cells. A form of non-Hodgkin's lymphoma is characterized by a chromosomal translocation t(2,5)(p23,q35) that involves NPM1 and ALK. The protein contains 1 LDL-receptor class A domain and 2 putative MAM domains.

Molekulargewicht: 176442

NCBI Accession: NP_004295

UniProt: Q9UM73

Pathways: RTK Signalweg