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ATG16L1 Antikörper

ATG16L1 Reaktivität: Human WB, IHC (p) Wirt: Maus Monoclonal 54CT27-2-6 unconjugated
Produktnummer ABIN6243484
  • Target Alle ATG16L1 Antikörper anzeigen
    ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))
    Reaktivität
    • 79
    • 34
    • 32
    • 11
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 67
    • 11
    • 1
    Maus
    Klonalität
    • 61
    • 18
    Monoklonal
    Konjugat
    • 49
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Dieser ATG16L1 Antikörper ist unkonjugiert
    Applikation
    • 53
    • 26
    • 25
    • 10
    • 10
    • 10
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    Immunogen
    Purified His-tagged ATG16L1 protein(Fragment) was used to produced this monoclonal antibody.
    Klon
    54CT27-2-6
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product ATG16L1 Primärantikörper
  • Applikationshinweise
    WB: 1:60. IHC-P: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Martinez-Outschoorn, Trimmer, Lin, Whitaker-Menezes, Chiavarina, Zhou, Wang, Pavlides, Martinez-Cantarin, Capozza, Witkiewicz, Flomenberg, Howell, Pestell, Caro, Lisanti, Sotgia: "Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment." in: Cell cycle (Georgetown, Tex.), Vol. 9, Issue 17, pp. 3515-33, (2010) (PubMed).

  • Target
    ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))
    Andere Bezeichnung
    ATG16L1 (ATG16L1 Produkte)
    Hintergrund
    The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.
    Molekulargewicht
    68265
    NCBI Accession
    NP_001177195, NP_001177196, NP_060444, NP_110430, NP_942593
    UniProt
    Q676U5
    Pathways
    Autophagie
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