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FZD10 Antikörper (N-Term)

FZD10 Reaktivität: Maus WB Wirt: Kaninchen Polyclonal RB52084 unconjugated
Produktnummer ABIN6243622
  • Target Alle FZD10 Antikörper anzeigen
    FZD10 (Frizzled Family Receptor 10 (FZD10))
    Bindungsspezifität
    • 15
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 177-212, N-Term
    Reaktivität
    • 44
    • 39
    • 19
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    Maus
    Wirt
    • 47
    Kaninchen
    Klonalität
    • 46
    • 1
    Polyklonal
    Konjugat
    • 19
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FZD10 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 14
    • 13
    • 13
    • 8
    • 6
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This FZD10 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 177-212 amino acids from the N-terminal region of human FZD10.
    Klon
    RB52084
    Isotyp
    Ig Fraction
    Top Product
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  • Applikationshinweise
    WB: 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Target
    FZD10 (Frizzled Family Receptor 10 (FZD10))
    Andere Bezeichnung
    FZD10 (FZD10 Produkte)
    Hintergrund
    Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK- 3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
    Molekulargewicht
    65336
    UniProt
    Q9ULW2
    Pathways
    WNT Signalweg
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