This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This DLG2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 614-648 amino acids from the Central region of human DLG2.
PPP1R58 antikoerper, PSD-93 antikoerper, PSD93 antikoerper, chapsyn-110 antikoerper, A330103J02Rik antikoerper, B230218P12Rik antikoerper, B330007M19Rik antikoerper, Dlgh2 antikoerper, Gm1197 antikoerper, discs, large homolog 2 (Drosophila) antikoerper, discs large MAGUK scaffold protein 2 antikoerper, dlg2 antikoerper, DLG2 antikoerper, Dlg2 antikoerper
Hintergrund
Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses (By similarity).