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PERK Antikörper (AA 530-850)

EIF2AK3 Reaktivität: Human, Maus, Ratte WB Wirt: Maus Monoclonal 1385CT582-4-39 unconjugated
Produktnummer ABIN6243642
  • Target Alle PERK (EIF2AK3) Antikörper anzeigen
    PERK (EIF2AK3) (Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3))
    Bindungsspezifität
    • 16
    • 16
    • 11
    • 9
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 530-850
    Reaktivität
    • 111
    • 71
    • 70
    • 16
    • 16
    Human, Maus, Ratte
    Wirt
    • 104
    • 4
    • 3
    • 1
    Maus
    Klonalität
    • 108
    • 4
    Monoklonal
    Konjugat
    • 35
    • 12
    • 9
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser PERK Antikörper ist unkonjugiert
    Applikation
    • 75
    • 54
    • 41
    • 28
    • 26
    • 26
    • 13
    • 9
    • 8
    • 6
    • 6
    • 4
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    Immunogen
    This EIF2AK3 antibody is generated from a mouse immunized with a recombinant protein conjugated synthetic peptide between 530-850 amino acids from human EIF2AK3.
    Klon
    1385CT582-4-39
    Isotyp
    IgG1
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    Discover our top product EIF2AK3 Primärantikörper
  • Applikationshinweise
    WB: 1:250-1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Target
    PERK (EIF2AK3) (Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3))
    Andere Bezeichnung
    EIF2AK3 (EIF2AK3 Produkte)
    Synonyme
    EIF2AK3 antikoerper, AI427929 antikoerper, Pek antikoerper, Perk antikoerper, PEK antikoerper, PERK antikoerper, WRS antikoerper, eukaryotic translation initiation factor 2 alpha kinase 3 antikoerper, EIF2AK3 antikoerper, Eif2ak3 antikoerper
    Hintergrund
    Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin-D1 (CCND1). Involved in control of mitochondrial morphology and function (By similarity).
    Molekulargewicht
    125216
    UniProt
    Q9NZJ5
    Pathways
    Hormone Transport, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Unfolded Protein Response
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