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EPH Receptor B1 Antikörper (AA 374-409)

EPHB1 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal RB50839 unconjugated
Produktnummer ABIN6243653
  • Target Alle EPH Receptor B1 (EPHB1) Antikörper anzeigen
    EPH Receptor B1 (EPHB1)
    Bindungsspezifität
    • 22
    • 15
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 374-409
    Reaktivität
    • 57
    • 47
    • 40
    • 1
    Human, Maus, Ratte
    Wirt
    • 64
    • 4
    • 4
    Kaninchen
    Klonalität
    • 70
    • 2
    Polyklonal
    Konjugat
    • 31
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EPH Receptor B1 Antikörper ist unkonjugiert
    Applikation
    • 62
    • 27
    • 27
    • 27
    • 13
    • 12
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    C
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This Mouse Ephb1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 374-409 amino acids from the Central region of Mouse Ephb1.
    Klon
    RB50839
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product EPHB1 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Target
    EPH Receptor B1 (EPHB1)
    Andere Bezeichnung
    Ephb1 (EPHB1 Produkte)
    Synonyme
    ELK antikoerper, EPHT2 antikoerper, Hek6 antikoerper, NET antikoerper, ephb1-a antikoerper, xek antikoerper, Xek antikoerper, MGC89790 antikoerper, EPHB1 antikoerper, CEK6 antikoerper, EK6 antikoerper, 9330129L11 antikoerper, AW488255 antikoerper, C130099E04Rik antikoerper, Cek6 antikoerper, ENSMUSG00000074119 antikoerper, Elk antikoerper, Elkh antikoerper, Net antikoerper, Ephb2 antikoerper, Erk antikoerper, elk antikoerper, EPH receptor B1 antikoerper, EPH receptor B1 S homeolog antikoerper, ephrin type-B receptor 1 antikoerper, Eph receptor B1 antikoerper, EPHB1 antikoerper, ephb1.S antikoerper, ephb1 antikoerper, LOC100467687 antikoerper, Ephb1 antikoerper
    Hintergrund
    Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Cognate/functional ephrin ligands for this receptor include EFNB1, EFNB2 and EFNB3. During nervous system development, regulates retinal axon guidance redirecting ipsilaterally ventrotemporal retinal ganglion cells axons at the optic chiasm midline. This probably requires repulsive interaction with EFNB2. In the adult nervous system together with EFNB3, regulates chemotaxis, proliferation and polarity of the hippocampus neural progenitors. Beside its role in axon guidance plays also an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and synapse formation. May also regulate angiogenesis. More generally, may play a role in targeted cell migration and adhesion. Upon activation by EFNB1 and probably other ephrin-B ligands activates the MAPK/ERK and the JNK signaling cascades to regulate cell migration and adhesion respectively.
    Molekulargewicht
    109881
    UniProt
    Q8CBF3
    Pathways
    RTK Signalweg
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