NGEF Antikörper (C-Term)
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- Target Alle NGEF Antikörper anzeigen
- NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))
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Bindungsspezifität
- AA 669-704, C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NGEF Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This NGEF antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 669-704 amino acids from the C-terminal region of human NGEF.
- Klon
- RB53235
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product NGEF Primärantikörper
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anti-Neuronal Guanine Nucleotide Exchange Factor (NGEF) (AA 612-710) antibody
NGEF Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 6E7 unconjugated
anti-Neuronal Guanine Nucleotide Exchange Factor (NGEF) (AA 495-710) antibodyNGEF Reaktivität: Human ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Neuronal Guanine Nucleotide Exchange Factor (NGEF) (AA 187-220), (N-Term) antibodyNGEF Reaktivität: Human, Ratte WB Wirt: Kaninchen Polyclonal RB53236 unconjugated
anti-Neuronal Guanine Nucleotide Exchange Factor (NGEF) (AA 429-710) antibodyNGEF Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB: 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
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- Target
- NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))
- Andere Bezeichnung
- NGEF (NGEF Produkte)
- Synonyme
- Ephexin-1 antikoerper, ARHGEF27 antikoerper, EPHEXIN antikoerper, Tims2 antikoerper, ephexin antikoerper, Besh3 antikoerper, ephexin-1 antikoerper, neuronal guanine nucleotide exchange factor antikoerper, NGEF antikoerper, Ngef antikoerper
- Hintergrund
- Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity).
- Molekulargewicht
- 82496
- UniProt
- Q8N5V2
- Pathways
- Neurotrophin Signalübertragung
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