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SNW1 Antikörper (AA 464-497)

SNW1 Reaktivität: Human, Maus WB, IF Wirt: Kaninchen Polyclonal RB54232 unconjugated
Produktnummer ABIN6243922
  • Target Alle SNW1 Antikörper anzeigen
    SNW1 (SNW Domain Containing 1 (SNW1))
    Bindungsspezifität
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 464-497
    Reaktivität
    • 14
    • 9
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 14
    Kaninchen
    Klonalität
    • 14
    Polyklonal
    Konjugat
    • 14
    Dieser SNW1 Antikörper ist unkonjugiert
    Applikation
    • 12
    • 8
    • 7
    • 4
    • 4
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This SNW1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 464-497 amino acids from human SNW1.
    Klon
    RB54232
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product SNW1 Primärantikörper
  • Applikationshinweise
    IF: 1:25. WB: 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Target
    SNW1 (SNW Domain Containing 1 (SNW1))
    Andere Bezeichnung
    SNW1 (SNW1 Produkte)
    Synonyme
    Gle1l1 antikoerper, Skiip antikoerper, bx42 antikoerper, ncoa-62 antikoerper, prp45 antikoerper, prpf45 antikoerper, skiip antikoerper, skip antikoerper, Bx42 antikoerper, NCOA-62 antikoerper, PRPF45 antikoerper, Prp45 antikoerper, SKIIP antikoerper, SKIP antikoerper, 2310008B08Rik antikoerper, AW048543 antikoerper, NCoA-62 antikoerper, SNW domain containing 1 antikoerper, nuclear protein SkiP antikoerper, puff-specific protein Bx42 antikoerper, putative nuclear protein SkiP antikoerper, GLE1 RNA export mediator homolog (yeast), pseudogene 1 antikoerper, SNW domain containing 1 S homeolog antikoerper, snw1 antikoerper, PVX_002605 antikoerper, LOC5564605 antikoerper, Smp_105860 antikoerper, UREG_03916 antikoerper, Gle1-ps1 antikoerper, snw1.S antikoerper, SNW1 antikoerper, Snw1 antikoerper
    Hintergrund
    Involved in transcriptional regulation. Modulates TGF- beta-mediated transcription via association with SMAD proteins, MYOD1-mediated transcription via association with PABPN1, RB1- mediated transcriptional repression, and retinoid-X receptor (RXR)- and vitamin D receptor (VDR)-dependent gene transcription in a cell line-specific manner probably involving coactivators NCOA1 and GRIP1. Is involved in NOTCH1-mediated transcriptional activation. Binds to multimerized forms of Notch intracellular domain (NICD) and is proposed to recruit transcriptional coactivators such as MAML1 to form an intermediate preactivation complex which associates with DNA-bound CBF-1/RBPJ to form a transcriptional activation complex by releasing SNW1 and redundant NOTCH1 NICD. Proposed to be involved in transcriptional activation by EBV EBNA2 of CBF-1/RBPJ-repressed promoters. Is recruited by HIV-1 Tat to Tat:P-TEFb:TAR RNA complexes and is involved in Tat transcription by recruitment of MYC, MEN1 and TRRAP to the HIV promoter. Functions as a splicing factor in pre-mRNA splicing. Is required in the specific splicing of CDKN1A pre-mRNA, the function probbaly involves the recruitment of U2AF2 to the mRNA. Is proposed to recruit PPIL1 to the spliceosome. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.
    Molekulargewicht
    61494
    UniProt
    Q13573
    Pathways
    Retinoic Acid Receptor Signaling Pathway
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