SOX7 Antikörper (AA 224-258)

Produktnummer ABIN6244006

Produktdetails anti-SOX7 Antikörper

Target: SOX7 (SRY (Sex Determining Region Y)-Box 7 (SOX7))

Bindungsspezifität: AA 224-258

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOX7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SOX7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 224-258 amino acids from the Central region of human SOX7.

Klon: RB51583

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu SOX7

Target: SOX7 (SRY (Sex Determining Region Y)-Box 7 (SOX7))

Andere Bezeichnung: SOX7 (SOX7 Produkte)

Synonyme: sox7-A antikoerper, xSox7 antikoerper, SRY-box 7 antikoerper, SRY (sex determining region Y)-box 7 antikoerper, SRY box 7 antikoerper, SRY-box 7 L homeolog antikoerper, SOX7 antikoerper, Sox7 antikoerper, sox7 antikoerper, sox7.L antikoerper

Hintergrund: Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors (By similarity). May be required for the survival of both hematopoietic and endothelial precursors during specification (By similarity). Competes with GATA4 for binding and activation of the FGF3 promoter (By similarity). Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation. Binds the DNA sequence 5'- AACAAT-3'.

Molekulargewicht: 42197

UniProt: Q9BT81

Pathways: Positive Regulation of Endopeptidase Activity