VAMP8 Antikörper (N-Term)

Produktnummer ABIN6244033

Produktdetails anti-VAMP8 Antikörper

Target: VAMP8 (Vesicle-Associated Membrane Protein 8 (Endobrevin) (VAMP8))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser VAMP8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This VAMP8 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 2~24 amino acids from the N-terminal region of human VAMP8.

Klon: 1414CT354-12-23-93

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: WB: 1:1000-1:2000. IHC-P: 1:25

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu VAMP8

Target: VAMP8 (Vesicle-Associated Membrane Protein 8 (Endobrevin) (VAMP8))

Andere Bezeichnung: VAMP8 (VAMP8 Produkte)

Synonyme: vamp8 antikoerper, EDB antikoerper, VAMP-8 antikoerper, AU041171 antikoerper, Edb antikoerper, endobrevin antikoerper, wu:fa18d07 antikoerper, zgc:56588 antikoerper, vesicle associated membrane protein 8 antikoerper, vesicle-associated membrane protein 8 (endobrevin) antikoerper, vesicle-associated membrane protein 8 antikoerper, vamp8 antikoerper, VAMP8 antikoerper, Vamp8 antikoerper

Hintergrund: SNAREs, Soluble N-ethylmaleimide-sensitive factor- attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Also required for dense-granule secretion in platelets. Plays also a role in regulated enzyme secretion in pancreatic acinar cells. Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells. Involved in the homotypic fusion of early and late endosomes.

Molekulargewicht: 11438

UniProt: Q9BV40