VANGL2 Antikörper (AA 376-410)

Produktnummer ABIN6244034

Produktdetails anti-VANGL2 Antikörper

Target: VANGL2 (Vang-Like 2 (VANGL2))

Bindungsspezifität: AA 376-410

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VANGL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This VANGL2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 376-410 amino acids from human VANGL2.

Klon: RB52981

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu VANGL2

Target: VANGL2 (Vang-Like 2 (VANGL2))

Andere Bezeichnung: VANGL2 (VANGL2 Produkte)

Hintergrund: Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. Required for cell surface localization of FZD3 and FZD6 in the inner ear (By similarity).

Molekulargewicht: 59714

UniProt: Q9ULK5

Pathways: WNT Signalweg, Stem Cell Maintenance, Tube Formation, Asymmetric Protein Localization