RSPO1 Antikörper (AA 206-240)
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- Target Alle RSPO1 Antikörper anzeigen
- RSPO1 (R-Spondin 1 (RSPO1))
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Bindungsspezifität
- AA 206-240
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RSPO1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This RSPO1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 206-240 amino acids from human RSPO1.
- Klon
- RB54226
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product RSPO1 Primärantikörper
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- Applikationshinweise
- WB: 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
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- Target
- RSPO1 (R-Spondin 1 (RSPO1))
- Andere Bezeichnung
- RSPO1 (RSPO1 Produkte)
- Synonyme
- RGD1565558 antikoerper, CRISTIN3 antikoerper, RSPO antikoerper, R-spondin antikoerper, Rspondin antikoerper, wu:fj81e05 antikoerper, zgc:92153 antikoerper, R-spondin 1 antikoerper, Rspo1 antikoerper, RSPO1 antikoerper, LOC100049655 antikoerper, rspo1 antikoerper
- Hintergrund
- Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway. Has a essential roles in ovary determination.
- Molekulargewicht
- 28959
- UniProt
- Q2MKA7
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