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RSPO1 Antikörper (AA 206-240)

RSPO1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB54226 unconjugated
Produktnummer ABIN6244080
  • Target Alle RSPO1 Antikörper anzeigen
    RSPO1 (R-Spondin 1 (RSPO1))
    Bindungsspezifität
    • 15
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    AA 206-240
    Reaktivität
    • 43
    • 39
    • 34
    • 15
    • 15
    • 15
    • 15
    • 15
    Human
    Wirt
    • 46
    • 6
    • 1
    Kaninchen
    Klonalität
    • 47
    • 6
    Polyklonal
    Konjugat
    • 22
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser RSPO1 Antikörper ist unkonjugiert
    Applikation
    • 36
    • 15
    • 13
    • 11
    • 11
    • 8
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This RSPO1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 206-240 amino acids from human RSPO1.
    Klon
    RB54226
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product RSPO1 Primärantikörper
  • Applikationshinweise
    WB: 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Target
    RSPO1 (R-Spondin 1 (RSPO1))
    Andere Bezeichnung
    RSPO1 (RSPO1 Produkte)
    Synonyme
    RGD1565558 antikoerper, CRISTIN3 antikoerper, RSPO antikoerper, R-spondin antikoerper, Rspondin antikoerper, wu:fj81e05 antikoerper, zgc:92153 antikoerper, R-spondin 1 antikoerper, Rspo1 antikoerper, RSPO1 antikoerper, LOC100049655 antikoerper, rspo1 antikoerper
    Hintergrund
    Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway. Has a essential roles in ovary determination.
    Molekulargewicht
    28959
    UniProt
    Q2MKA7
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