TMEM106B Antikörper (AA 218-252)

Produktnummer ABIN6244143

Produktdetails anti-TMEM106B Antikörper

Target: TMEM106B (Transmembrane Protein 106B (TMEM106B))

Bindungsspezifität: AA 218-252

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMEM106B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Homologie: B, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TMEM106B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 218-252 amino acids from human TMEM106B.

Klon: RB56763

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000. FC: 1:25

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-TMEM106B Antikörper (ABIN6244143)

Jiang, Cao, Sawaya, Abskharon, Ge, DeTure, Dickson, Fu, Ogorzalek Loo, Loo, Eisenberg: "Amyloid fibrils in FTLD-TDP are composed of TMEM106B and not TDP-43." in: Nature, Vol. 605, Issue 7909, pp. 304-309, (2022) (PubMed).

Details zu TMEM106B

Target: TMEM106B (Transmembrane Protein 106B (TMEM106B))

Andere Bezeichnung: TMEM106B (TMEM106B Produkte)

Hintergrund: Involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking via its interaction with MAP6. May act by inhibiting retrograde transport of lysosomes along dendrites. Required for dendrite branching.

Molekulargewicht: 31127

UniProt: Q9NUM4