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ATG10 Antikörper (N-Term)

ATG10 Reaktivität: Human IHC (p) Wirt: Kaninchen Polyclonal RB7550 unconjugated
Produktnummer ABIN6244154
  • Target Alle ATG10 Antikörper anzeigen
    ATG10 (Autophagy Related 10 (ATG10))
    Bindungsspezifität
    • 15
    • 13
    • 8
    • 8
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    AA 15-45, N-Term
    Reaktivität
    • 70
    • 14
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 68
    • 1
    • 1
    Kaninchen
    Klonalität
    • 68
    • 2
    Polyklonal
    Konjugat
    • 26
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ATG10 Antikörper ist unkonjugiert
    Applikation
    • 35
    • 27
    • 25
    • 13
    • 13
    • 9
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This ATG10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15~45 amino acids from the N-term of human APG10L.
    Klon
    RB7550
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product ATG10 Primärantikörper
  • Applikationshinweise
    IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Sanchez, Penfornis, Oskowitz, Boonjindasup, Cai, Dhule, Rowan, Kelekar, Krause, Pochampally: "Activation of autophagy in mesenchymal stem cells provides tumor stromal support." in: Carcinogenesis, Vol. 32, Issue 7, pp. 964-72, (2011) (PubMed).

  • Target
    ATG10 (Autophagy Related 10 (ATG10))
    Andere Bezeichnung
    ATG10 (ATG10 Produkte)
    Synonyme
    APG10 antikoerper, APG10L antikoerper, pp12616 antikoerper, Atg10 antikoerper, ATG10 antikoerper, MGC123341 antikoerper, im:7153729 antikoerper, zgc:123341 antikoerper, ATATG10 antikoerper, autophagy 10 antikoerper, DDBDRAFT_0190076 antikoerper, DDBDRAFT_0252608 antikoerper, DDB_0190076 antikoerper, DDB_0252608 antikoerper, 5330424L23Rik antikoerper, 5430428K15Rik antikoerper, AI852123 antikoerper, Agp10 antikoerper, Apg10l antikoerper, Apg10p antikoerper, Atg10l antikoerper, autophagy related 10 antikoerper, autophagy-related 10 antikoerper, AuTophaGy (yeast Atg homolog) antikoerper, ATG10 autophagy related 10 homolog (S. cerevisiae) antikoerper, autophagocytosis-associated family protein antikoerper, E2-like conjugating enzyme antikoerper, hypothetical protein antikoerper, autophagy protein 10 antikoerper, autophagy-related protein 10 antikoerper, ATG10 antikoerper, Atg10 antikoerper, atg-10 antikoerper, atg10 antikoerper, CAALFM_C302930WA antikoerper, APG10 antikoerper
    Hintergrund
    Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG10 is an ATG12-conjugating enzyme (E2-like enzyme) that likely serves as an ATG5-recognition molecule. This protein interacts with MAP1LC3A. By interacting with MAP1LC3A, it plays a role in the conjugation of ATG12 to ATG5. APG10 also is able to directly interact either with ATG5 or ATG7.
    Molekulargewicht
    25279
    NCBI Accession
    NP_001124500, NP_113670
    UniProt
    Q9H0Y0
    Pathways
    ER-Nucleus Signaling, Autophagie
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