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DKK2 Antikörper

DKK2 Reaktivität: Human, Maus WB Wirt: Maus Monoclonal 1833CT856-7-20 unconjugated
Produktnummer ABIN6244156
  • Target Alle DKK2 Antikörper anzeigen
    DKK2 (Dickkopf 2 Homolog (DKK2))
    Reaktivität
    • 55
    • 14
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 51
    • 3
    • 1
    Maus
    Klonalität
    • 52
    • 3
    Monoklonal
    Konjugat
    • 27
    • 8
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DKK2 Antikörper ist unkonjugiert
    Applikation
    • 43
    • 29
    • 27
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    Immunogen
    This DKK2 antibody is generated from a mouse immunized with a recombinant protein of human DKK2.
    Klon
    1833CT856-7-20
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product DKK2 Primärantikörper
  • Applikationshinweise
    WB: 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Target
    DKK2 (Dickkopf 2 Homolog (DKK2))
    Andere Bezeichnung
    DKK2 (DKK2 Produkte)
    Synonyme
    DKK-2 antikoerper, Dkk4 antikoerper, zgc:171574 antikoerper, dickkopf WNT signaling pathway inhibitor 2 antikoerper, DKK2 antikoerper, Dkk2 antikoerper, dkk2 antikoerper
    Hintergrund
    Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
    Molekulargewicht
    28447
    UniProt
    Q9UBU2
    Pathways
    WNT Signalweg
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