This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This SLC5A12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 576-605 amino acids from the C-terminal region of human SLC5A12.
AI315119 antikoerper, D630015G19 antikoerper, SMCT2 antikoerper, solute carrier family 5 (sodium/glucose cotransporter), member 12 antikoerper, solute carrier family 5 member 12 antikoerper, Slc5a12 antikoerper, SLC5A12 antikoerper
Hintergrund
Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na(+)-coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the high-affinity Na(+)-coupled lactate transporter SLC5A8 (MIM 608044) in the distal proximal tubule (Gopal et al., 2007 [PubMed 17692818]).