Mare/Nprl3/C16orf35 Antikörper (AA 86-117)

Produktnummer ABIN6244303

Produktdetails anti-Mare/Nprl3/C16orf35 Antikörper

Target: Mare/Nprl3/C16orf35 (C16orf35) (MARE (C16orf35))

Bindungsspezifität: AA 86-117

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Mare/Nprl3/C16orf35 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NPRL3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 86-117 amino acids from human NPRL3.

Klon: RB54296

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu Mare/Nprl3/C16orf35

Target: Mare/Nprl3/C16orf35 (C16orf35) (MARE (C16orf35))

Andere Bezeichnung: NPRL3 (C16orf35 Produkte)

Hintergrund: As a component of the GATOR1 complex, inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC- containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling.

Molekulargewicht: 63605

UniProt: Q12980