CD28 Antikörper
-
- Target Alle CD28 Antikörper anzeigen
- CD28
-
Reaktivität
- Human, Maus, Rind (Kuh), Schwein, Schaf
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser CD28 Antikörper ist unkonjugiert
-
Applikation
- Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)
- Aufreinigung
- Protein G affinity chromatography
- Immunogen
- Stimulated human leukocytes were used as the immunogen for the CD28 antibody.
- Klon
- 204-12
- Isotyp
- IgG2a kappa
- Top Product
- Discover our top product CD28 Primärantikörper
-
-
- Applikationshinweise
-
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Functional Activity (Order SAF formulation)
Optimal dilution of the CD28 antibody should be determined by the researcher. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 0.2 mg/mL
- Buffer
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
-
- Target
- CD28
- Andere Bezeichnung
- CD28 (CD28 Produkte)
- Synonyme
- Tp44 antikoerper, CD28RNA antikoerper, cd28 antikoerper, CD28 molecule antikoerper, CD28 antigen antikoerper, Cd28 molecule antikoerper, CD28 molecule L homeolog antikoerper, CD28 antikoerper, Cd28 antikoerper, cd28.L antikoerper
- Hintergrund
- Recognizes a glycoprotein of 44-88 kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.
- Gen-ID
- 920
- UniProt
- P10747
- Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
-