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CD4 Antikörper (mFluor™450)

Name: CD4 Antikörper (mFluor™450)
SKU: ABIN6253117
Price: 369.09 EUR
Availability: InStock

GMP Grade CD4 Reaktivität: Human, Rhesusaffen, Cynomolgus FACS Wirt: Maus Monoclonal OKT4 mFluor™450

FACS

Lymphocytes gated blood (RBC lysed) stained with mFluor 450 conjugated anti-human CD4 (clone OKT-4, red histogram). (CD4 Antikörper (mFluor™450))

2 Abbildungen

Produktnummer ABIN6253117

Datenblatt (PDF)

Target Alle CD4 Antikörper anzeigen

CD4
Reaktivität
364

225

119

48

24

21

19

19

18

12

10

10

10

10

10

9

9

9

9

5

4

3

2

1

1

1

1

1
Human, Rhesusaffen, Cynomolgus
Wirt
378

150

136

3

3

1
Maus
Passende Sekundärantikörper
Klonalität
526

139

3
Monoklonal
Konjugat
217

76

67

51

37

19

15

14

11

10

9

9

9

8

6

5

5

4

4

4

4

4

4

4

4

4

4

4

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1
Dieser CD4 Antikörper ist konjugiert mit mFluor™450
Applikation
533

208

147

118

99

81

73

42

39

36

33

27

17

10

10

9

9

7

6

6

5

4

4

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1
Flow Cytometry (FACS)

Verwendungszweck

CD4 mFluor™ 450 Antibody

Produktmerkmale

CD4 is a 55kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. It is a specific marker for T lymphocytes, monocytes, macrophages, and dendritic cells. Through interaction of MHC-II, CD4 facilitates cell-cell interaction, thymic differentiation, and activation of downstream signaling cascades. HIV infection of T-cells is instigated through binding of HIV to CD4. The OKT4 binds to the D3 domain of CD4 and does not inhibit HIV binding.

Aufreinigung

Purified

Reinheit

>95 %

Güteklasse

GMP Grade

Immunogen

Human peripheral blood T lymphocytes

Klon

OKT4

Isotyp

IgG2b, kappa

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Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C

Informationen zur Lagerung

2-8°C, Conjugated antibodies should never be frozen.
Target

CD4

Andere Bezeichnung

CD4 (CD4 Produkte)

NCBI Accession

NM_000616

UniProt

P01730

Pathways

T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events