VCAM1 Antikörper
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- Target Alle VCAM1 Antikörper anzeigen
- VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser VCAM1 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Spezifität
- B-K9 produces mouse IgG1 immunoglobulins directed against a 110 kD protein known as human CD106. It reacts with approximately 15% of peripheral lymphocytes and between 30-90% activated HUVEC
- Reinheit
- PURE
- Klon
- B-K9
- Isotyp
- IgG1
- Top Product
- Discover our top product VCAM1 Primärantikörper
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- Applikationshinweise
- tochemistry on cytospots, immunohistochemistry on frozen tissue sections
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Lagerung
- 4 °C
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- Target
- VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
- Andere Bezeichnung
- CD106 (VCAM1 Produkte)
- Synonyme
- CD106 antikoerper, INCAM-100 antikoerper, Vcam-1 antikoerper, VCAM1B antikoerper, fi76d06 antikoerper, wu:fi76d06 antikoerper, zgc:158875 antikoerper, VCAM1 antikoerper, vascular cell adhesion molecule 1 antikoerper, vascular cell adhesion molecule 1b antikoerper, VCAM1 antikoerper, Vcam1 antikoerper, vcam1b antikoerper, VCAM-1 antikoerper
- Hintergrund
- Antigen distribution: CD106 antigen binds the integrins a4b1 (CD49d/CD29, VLA-4) and a4b7 [4]. VLA-4 is the dominant ligand in cells expressing both integrins. Endothelial CD106 contributes to the extravasation of lymphocytes, monocytes, basophils and eosinophils (but not neutrophils) from blood vessels, especially at sites of inflammation. The VLA-4 interaction can mediate both the initial tethering and rolling of lymphocytes on endothelium as well as their subsequent arrest and firm adhesion [5]. CD106 expression on non-vascular tissues is thought to play a role in the interaction of hematopoietic progenitors with bone marrow stromal cells, B cell binding to follicular dendritic cells, co-stimulation of T cells and embryonic development [1,2,3]. Cellular Expression: VCAM-1. Vascular endothelium, dendritic cells, macrophages
- Pathways
- Carbohydrate Homeostasis
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