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Histone H3.1 Antikörper (pSer10)

HIST1H3B Reaktivität: Human, Maus, Ratte WB, IHC, IF, ELISA, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6254919
  • Target Alle Histone H3.1 (HIST1H3B) Antikörper anzeigen
    Histone H3.1 (HIST1H3B)
    Bindungsspezifität
    • 16
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer10
    Reaktivität
    • 48
    • 16
    • 16
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 45
    • 3
    • 2
    Kaninchen
    Klonalität
    • 45
    • 5
    Polyklonal
    Konjugat
    • 38
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Histone H3.1 Antikörper ist unkonjugiert
    Applikation
    • 37
    • 29
    • 26
    • 16
    • 15
    • 11
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)
    Spezifität
    Phospho-Histone H3.1 (Ser10) Antibody detects endogenous levels of Histone H3.1 only when phosphorylated at Serine 10
    Kreuzreaktivität
    Human, Maus, Ratte (Rattus)
    Aufreinigung
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    Immunogen
    A synthesized peptide derived from human Histone H3.1 around the phosphorylation site of Serine 10
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:500-1:2000 IHC 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C.Stable for 12 months from date of receipt
    Haltbarkeit
    12 months
  • Liang, Sun, Zhao, Zhang, Gu, Dong, Zhang, Sun, Sun: "Rictor regulates the vasculogenic mimicry of melanoma via the AKT-MMP-2/9 pathway." in: Journal of cellular and molecular medicine, Vol. 21, Issue 12, pp. 3579-3591, (2018) (PubMed).

    Wu, Wang, Yang, Huang, Hu, Shu, Zhang, Zheng: "MAD2-p31comet axis deficiency reduces cell proliferation, migration and sensitivity of microtubule-interfering agents in glioma." in: Biochemical and biophysical research communications, Vol. 498, Issue 1, pp. 157-163, (2018) (PubMed).

  • Target
    Histone H3.1 (HIST1H3B)
    Andere Bezeichnung
    Histone H3.1 (HIST1H3B Produkte)
    Synonyme
    H3 histone antikoerper, Hist1h2ai antikoerper, histone cluster 1, H2ai-like1 antikoerper, histone H3.1 antikoerper, Hht21p antikoerper, Hist1h2ail1 antikoerper, H3.1 antikoerper, HHT21 antikoerper
    Hintergrund

    Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

    Gene: HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J

    Molekulargewicht
    17kDa
    Gen-ID
    8, 350, 835
    UniProt
    P68431, Q71DI3, P84243
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