Histone H3.1 Antikörper (pSer10)
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- Target Alle Histone H3.1 (HIST1H3B) Antikörper anzeigen
- Histone H3.1 (HIST1H3B)
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Bindungsspezifität
- pSer10
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Histone H3.1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)
- Spezifität
- Phospho-Histone H3.1 (Ser10) Antibody detects endogenous levels of Histone H3.1 only when phosphorylated at Serine 10
- Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
- Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
- Immunogen
- A synthesized peptide derived from human Histone H3.1 around the phosphorylation site of Serine 10
- Isotyp
- IgG
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- Applikationshinweise
- WB 1:500-1:2000 IHC 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
- Haltbarkeit
- 12 months
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Rictor regulates the vasculogenic mimicry of melanoma via the AKT-MMP-2/9 pathway." in: Journal of cellular and molecular medicine, Vol. 21, Issue 12, pp. 3579-3591, (2018) (PubMed).
: "MAD2-p31comet axis deficiency reduces cell proliferation, migration and sensitivity of microtubule-interfering agents in glioma." in: Biochemical and biophysical research communications, Vol. 498, Issue 1, pp. 157-163, (2018) (PubMed).
: "
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Rictor regulates the vasculogenic mimicry of melanoma via the AKT-MMP-2/9 pathway." in: Journal of cellular and molecular medicine, Vol. 21, Issue 12, pp. 3579-3591, (2018) (PubMed).
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- Target
- Histone H3.1 (HIST1H3B)
- Andere Bezeichnung
- Histone H3.1 (HIST1H3B Produkte)
- Synonyme
- H3 histone antikoerper, Hist1h2ai antikoerper, histone cluster 1, H2ai-like1 antikoerper, histone H3.1 antikoerper, Hht21p antikoerper, Hist1h2ail1 antikoerper, H3.1 antikoerper, HHT21 antikoerper
- Hintergrund
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Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Gene: HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J
- Molekulargewicht
- 17kDa
- Gen-ID
- 8, 350, 835
- UniProt
- P68431, Q71DI3, P84243
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