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SNCA Antikörper (pSer129)

SNCA Reaktivität: Human, Ratte, Maus WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6254965
  • Target Alle SNCA Antikörper anzeigen
    SNCA (Synuclein, alpha (SNCA))
    Bindungsspezifität
    • 68
    • 29
    • 28
    • 17
    • 16
    • 15
    • 14
    • 11
    • 10
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer129
    Reaktivität
    • 294
    • 189
    • 188
    • 14
    • 10
    • 10
    • 9
    • 7
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 227
    • 105
    • 5
    • 3
    • 1
    • 1
    Kaninchen
    Klonalität
    • 216
    • 127
    Polyklonal
    Konjugat
    • 146
    • 24
    • 22
    • 16
    • 11
    • 8
    • 8
    • 7
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    Dieser SNCA Antikörper ist unkonjugiert
    Applikation
    • 226
    • 164
    • 110
    • 72
    • 68
    • 65
    • 56
    • 52
    • 48
    • 41
    • 23
    • 18
    • 10
    • 8
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    Phospho-Synuclein alpha (Ser129) Antibody detects endogenous levels of Synuclein alpha only when phosphorylated at Serine 129.
    Homologie
    Pig,Bovine,Horse,Rabbit,Dog,Chicken
    Aufreinigung
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    Immunogen
    A synthesized peptide derived from human Synuclein alpha around the phosphorylation site of Ser129.
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    SNCA (Synuclein, alpha (SNCA))
    Andere Bezeichnung
    SNCA (SNCA Produkte)
    Synonyme
    snca antikoerper, MGC64356 antikoerper, LOC619283 antikoerper, NACP antikoerper, alphaSYN antikoerper, PARK1 antikoerper, PARK4 antikoerper, PD1 antikoerper, synuclein alpha L homeolog antikoerper, alpha-synuclein antikoerper, synuclein alpha antikoerper, synuclein, alpha antikoerper, snca.L antikoerper, LOC619283 antikoerper, SNCA antikoerper, Snca antikoerper
    Hintergrund

    Description: May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.

    Gene: SNCA

    Molekulargewicht
    18kDa
    Gen-ID
    6622
    UniProt
    P37840
    Pathways
    Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
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