GATA1 Antikörper (pSer142)

Produktnummer ABIN6254982

Produktdetails anti-GATA1 Antikörper

Target: GATA1 (GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1))

Bindungsspezifität: pSer142

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GATA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Spezifität: Phospho-GATA1 (Ser142) Antibody detects endogenous levels of GATA1 only when phosphorylated at Serine 142.

Homologie: Pig,Sheep,Rabbit

Aufreinigung: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogen: A synthesized peptide derived from human GATA1 around the phosphorylation site of Ser142.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IP, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu GATA1

Target: GATA1 (GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1))

Andere Bezeichnung: GATA1 (GATA1 Produkte)

Synonyme: ERYF1 antikoerper, GATA-1 antikoerper, GF-1 antikoerper, GF1 antikoerper, NF-E1 antikoerper, NFE1 antikoerper, XLANP antikoerper, XLTDA antikoerper, XLTT antikoerper, Gata-1 antikoerper, Gf-1 antikoerper, eryf1 antikoerper, Eryf1 antikoerper, GATA1 antikoerper, gata-1 antikoerper, Gata1 antikoerper, si:dkeyp-77f7.5 antikoerper, gata1 antikoerper, gata1a-A antikoerper, xGATA-1 antikoerper, xgata1 antikoerper, XGATA-1B antikoerper, gata1b-A antikoerper, gta1 antikoerper, zg1 antikoerper, NF-E1a antikoerper, GATA binding protein 1 antikoerper, GATA binding protein 1 (globin transcription factor 1) antikoerper, amidase antikoerper, aspartyl/glutamyl-tRNA amidotransferase subunit A antikoerper, putative amidase antikoerper, GatA1 antikoerper, glutamyl-tRNA amidotransferase subunit A antikoerper, hematopietic transcription factor GATA-1 antikoerper, GATA binding protein 1b antikoerper, GATA binding protein 1 L homeolog antikoerper, GATA binding protein 1 S homeolog antikoerper, GATA binding protein 1a antikoerper, erythroid transcription factor antikoerper, GATA1 antikoerper, Gata1 antikoerper, gatA1 antikoerper, gata-1 antikoerper, gata1b antikoerper, gata1.L antikoerper, gata1.S antikoerper, gata1a antikoerper, LOC108348091 antikoerper

Hintergrund:

Description: Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS (PubMed:24245781).

Gene: GATA1

Molekulargewicht: 43kDa

Gen-ID: 2623

UniProt: P15976

Pathways: Cellular Response to Molecule of Bacterial Origin