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MITF Antikörper (pSer73, pSer180)

Name: MITF Antikörper (pSer73, pSer180)
SKU: ABIN6255037
Price: 720 EUR
Availability: InStock

MITF Reaktivität: Human, Maus, Ratte, Affe WB, IHC, IF, ELISA, ICC Wirt: Kaninchen Polyclonal unconjugated

Western blot analysis of MITF phosphorylation expression in COS7 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. (MITF Antikörper (pSer73, pSer180))

ABIN6267244 at 1/100 staining mouse brain tissue sections by IHC-P. (MITF Antikörper (pSer73, pSer180))

IHC

ABIN6267244 at 1/100 staining rat ovarian tissue sections by IHC-P. (MITF Antikörper (pSer73, pSer180))

IHC

Western blot analysis of Phospho-MITF (Ser180/73) expression in various lysates (MITF Antikörper (pSer73, pSer180))

10 Abbildungen

Produktnummer ABIN6255037

Datenblatt (PDF)

Target Alle MITF Antikörper anzeigen

MITF (Microphthalmia-Associated Transcription Factor (MITF))
Bindungsspezifität
19

15

12

8

8

7

4

4

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1
pSer73, pSer180
Reaktivität
103

49

24

17

5

5

5

4

4

4

4

3

2

2

2

2
Human, Maus, Ratte, Affe
Wirt
77

40

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
69

50
Polyklonal
Konjugat
64

8

4

4

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
Dieser MITF Antikörper ist unkonjugiert
Applikation
70

48

43

36

34

17

13

7

6

3

3

3

2

2

2

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)

Spezifität

Phospho-MITF (Ser180/73) Antibody detects endogenous levels of MITF only when phosphorylated at Serine 180/73

Kreuzreaktivität

Human, Affe, Maus, Ratte (Rattus)

Aufreinigung

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogen

A synthesized peptide derived from human MITF around the phosphorylation site of Serine 180/73

Isotyp

IgG

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anti-Microphthalmia-Associated Transcription Factor (MITF) (Ser180), (Ser73) antibody
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anti-Microphthalmia-Associated Transcription Factor (MITF) (AA 1-114) antibody
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anti-Microphthalmia-Associated Transcription Factor (MITF) antibody
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anti-Microphthalmia-Associated Transcription Factor (MITF) (AA 1-280) antibody
MITF Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated

anti-Microphthalmia-Associated Transcription Factor (MITF) (Ser180), (Ser73) antibody
MITF Reaktivität: Human, Maus WB, IHC, ELISA, IF/ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Microphthalmia-Associated Transcription Factor (MITF) (AA 1-520) antibody
MITF Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated

anti-Microphthalmia-Associated Transcription Factor (MITF) antibody
MITF Reaktivität: Human, Hund IHC, StM Wirt: Maus Monoclonal MITF-915 unconjugated

Applikationshinweise

WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20 °C.Stable for 12 months from date of receipt

Haltbarkeit

12 months
Target

MITF (Microphthalmia-Associated Transcription Factor (MITF))

Andere Bezeichnung

MITF (MITF Produkte)

Synonyme

MITF antikoerper, ws2a antikoerper, mitfa antikoerper, MITF-A antikoerper, LOC100313655 antikoerper, mitfb antikoerper, CMM8 antikoerper, MI antikoerper, WS2 antikoerper, WS2A antikoerper, bHLHe32 antikoerper, BCC2 antikoerper, Bhlhe32 antikoerper, Gsfbcc2 antikoerper, Vitiligo antikoerper, Wh antikoerper, bw antikoerper, mi antikoerper, vit antikoerper, MITF-H antikoerper, MITF-M antikoerper, CMI9 antikoerper, melanogenesis associated transcription factor antikoerper, microphthalmia-associated transcription factor antikoerper, microphthalmia-associated transcription factor S homeolog antikoerper, Microphthalmia antikoerper, MITF antikoerper, mitf antikoerper, LOC100313655 antikoerper, mitf.S antikoerper, LOC100534525 antikoerper, MICROP antikoerper, Mitf antikoerper

Hintergrund

Description: Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to M-boxes (5'-TCATGTG-3') and symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.
Gene: MITF

Molekulargewicht

52kDa

Gen-ID

4286

UniProt

O75030

Pathways

Chromatin Binding