HDAC6 Antikörper (pSer22)
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- Target Alle HDAC6 Antikörper anzeigen
- HDAC6 (Histone Deacetylase 6 (HDAC6))
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Bindungsspezifität
- pSer22
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser HDAC6 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- Phospho-HDAC6 (Ser22) Antibody detects endogenous levels of HDAC6 only when phosphorylated at Serine 22.
- Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
- Immunogen
- A synthesized peptide derived from human HDAC6 around the phosphorylation site of Ser22.
- Isotyp
- IgG
- Top Product
- Discover our top product HDAC6 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- HDAC6 (Histone Deacetylase 6 (HDAC6))
- Andere Bezeichnung
- HDAC6 (HDAC6 Produkte)
- Hintergrund
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Description: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
Gene: HDAC6
- Molekulargewicht
- 131kDa
- Gen-ID
- 10013
- UniProt
- Q9UBN7
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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