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PKM Antikörper (pSer37)

PKM Reaktivität: Human, Maus, Ratte ELISA, WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6255266
  • Target Alle PKM Antikörper anzeigen
    PKM (Pyruvate Kinase M1/2 (PKM))
    Bindungsspezifität
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer37
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 34
    • 5
    Kaninchen
    Klonalität
    • 33
    • 6
    Polyklonal
    Konjugat
    • 22
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PKM Antikörper ist unkonjugiert
    Applikation
    • 24
    • 18
    • 11
    • 9
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    Spezifität
    Phospho-PKM2 (Ser37) Antibody detects endogenous levels of PKM2 only when phosphorylated at Ser37.
    Homologie
    Pig,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus
    Aufreinigung
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    Immunogen
    A synthesized peptide derived from human PKM2 around the phosphorylation site of Ser37.
    Isotyp
    IgG
    Top Product
    Discover our top product PKM Primärantikörper
  • Applikationshinweise
    WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    PKM (Pyruvate Kinase M1/2 (PKM))
    Andere Bezeichnung
    PKM (PKM Produkte)
    Synonyme
    CTHBP antikoerper, OIP3 antikoerper, PK3 antikoerper, PKM2 antikoerper, TCB antikoerper, THBP1 antikoerper, AA414905 antikoerper, AL024370 antikoerper, AL024424 antikoerper, Pk-2 antikoerper, Pk-3 antikoerper, Pk3 antikoerper, Pkm2 antikoerper, PKM12 antikoerper, CG7070 antikoerper, Dmel\\CG7070 antikoerper, PYK antikoerper, Pyk antikoerper, cb1029 antikoerper, fj33f03 antikoerper, pkm2 antikoerper, pkm2a antikoerper, wu:fj33f03 antikoerper, MGC53388 antikoerper, PKM antikoerper, PK-S antikoerper, pk3 antikoerper, pkm2b antikoerper, zgc:92037 antikoerper, pyruvate kinase M1/2 antikoerper, pyruvate kinase, muscle antikoerper, Pyruvate kinase antikoerper, pyruvate kinase M1/2a antikoerper, pyruvate kinase PKM antikoerper, pyruvate kinase (PK) antikoerper, pyruvate kinase antikoerper, pyruvate kinase M1/2 S homeolog antikoerper, pyruvate kinase M1/2b antikoerper, PKM antikoerper, Pkm antikoerper, PyK antikoerper, pkma antikoerper, pkm antikoerper, LOC710798 antikoerper, pyk antikoerper, pk antikoerper, LOC100534543 antikoerper, pkm.S antikoerper, pkmb antikoerper
    Hintergrund

    Description: Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.

    Gene: PKM

    Molekulargewicht
    58 kDa
    Gen-ID
    5315
    UniProt
    P14618
    Pathways
    Warburg Effekt
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